Dynamic Structural Biology
Proteins are dynamic molecules. They move. They breathe. This movement enables their function. The diffUSE Project is building the methods, tools, and infrastructure to make protein motion visible, measurable, and usable — transforming how we discover drugs, design biology, and understand disease.
Reimagining How We Approach Science
We believe that unlocking protein dynamics requires not just new methods but also new ways we work together as scientists. By building openly, we aim to enable the collection of dynamic data at the scale and diversity needed to uncover the fundamental principles of biology.
Latest Posts from our Scientists
Is it all just the lattice?
Taylor’s update on his work in the diffUSE project and the roadmap to a complete forward model of diffuse scattering.
Cruel Kinase Summer, Episode 16
The Tortured Proteins Department Podcast, Cruel Kinase Summer
BANDICOOT: Coot 0.9 That Runs on MacOS Tahoe
Reviving Coot 0.9 for MacOS Tahoe as Bandicoot, a bespoke and integrated molecular modeling environment.
