Dynamic Structural Biology
Proteins are dynamic molecules. They move. They breathe. This movement enables their function. The diffUSE Project is building the methods, tools, and infrastructure to make protein motion visible, measurable, and usable — transforming how we discover drugs, design biology, and understand disease.
Reimagining How We Approach Science
We believe that unlocking protein dynamics requires not just new methods but also new ways we work together as scientists. By building openly, we aim to enable the collection of dynamic data at the scale and diversity needed to uncover the fundamental principles of biology.
Latest Posts from our Scientists
Displaying Conformational Heterogeneity in BANDICOOT
In preparation for hierarchical hetereogeneity encoding, BANDICOOT has a new, more intuitive display mode for alternate conformations.
mmCIF Explorer and the Heterogeneity Proposal
A playground for the PDBx/mmCIF file exploration, a look at the current proposal for encoding correlated heterogeneity
Is it all just the lattice?
Taylor’s update on his work in the diffUSE project and the roadmap to a complete forward model of diffuse scattering.
